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The models rely on self-assembly of skin components within an appropriate matrix
UVA exposure additionally degrades the dermal matrix through decreases in procollagen synthesis and increases in MMP-1, -3, and – 9 expression. Photoaged skin has also displayed reduced dermal vasculature and dermal connective tissue breakdown and disorganization in human explant cultures. Human Skin Equivalents are in vitro tissue models that have been previously used for studies on…
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The GFDL model does not predict any decreases in CWD
Even if there is increased precipitation and more excess water for any given month, this favors the partitioning of excess water into runoff because of the limitation of soil storage. Therefore, shorter wet seasons translate into reductions in recharge, and amount of runoff is related to if there is more or less precipitation. The dry…
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The modeling approach begins with the climate as precipitation and air temperature
The future condition analyses are for four climate scenarios representing a range of projected outcomes and model sensitivity to greenhouse gas forcing, and an analysis of the resulting hydrologic impacts. To develop confidence in the application of historic and future climate projections to hydrologic modeling, this paper evaluates the reliability of hydrologic model performance by…
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A non-significant chi-square statistic represents a good model fit to the data
The study’s treatment population of patients with diabetes was selected from the six pilot institutions implementing the CCM program, having physical yards of varying security and medication requirement levels. The control population was chosen from the remaining non-pilot prisons also having a complex mix of security and clinical needs. Individuals included in this research were…
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The practitioners chose the breakthrough series as their improvement strategy
The CSFs are well defined at the program level, at which level of analysis they detail the key metrics of success that guide the program. Qualitative differences in CSFs exist between private- and public-sector entities for the same types of programs . When a program from the private sector is adapted for use in the…
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Traditional publishers have had no choice but to follow the new entrants’ tactics
Wisely perceived, altruism is not self-sacrifice but rather enlightened self-interest . As the Dalai Lama put it, “If you’re going to be selfish, be wisely selfish—which means to love and serve others, since love and service to others bring rewards to oneself that otherwise would be unachievable” . These benefits of altruism hold major implications…
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The clinical variability in study design and outcome precluded performing a meta-analysis
Spike-RBD-Fc and trimeric Spike ectodomain , and ACE2-Fc were produced as biotinylated proteins as previously described.Fabs were subcloned from the Fab-phagemid into an E. coli expression vector pBL347. VH-Fc were cloned into a pFUSE vector with a human IgG1 Fc domain as previously described.The heavy chain of the IgG were cloned from the Fab plasmid into…
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The impacts of land use change on weather and climate have received increasing attention
The frequency response is determined from averaging the cross-spectra of the input output data. It is evident that the frequency response derived from the case with harder forcing deviates from the nominal, or low amplitude, frequency response. Additionally, the jet velocity coherence, shown in Fig. 3, decreases with the larger amplitude forcing compared to the nominal…
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Montello’s updated typology of regions can inform this subject
According to a survey carried out by Handley , “19 of the 60 countries that delimit constituencies indicated that respect for communities of interest was a criterion considered by the boundary authority” . That selection of countries includes such disparate nations as Australia, Germany, Hungary, Pakistan, Nepal, and Papua New Guinea, all defining the term…
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D-Amino acids are also important for synthesis of specialized metabolites
This review therefore focuses on the roles of organic N metabolites derived from microbes, as well as on the roles of pyridoxal-5′-phosphate -dependent enzymes, which constitute the primary family of enzymes responsible for N metabolism. Additionally, this review highlights potential applications of N metabolites and related gene products developed using synthetic biology to engineer new…